Vol.4 No.1 Serial No.12 January 25th 2004°°°°

°ĺCLC number°Ņ R™≤05; R743.34¬†°ĺDocumnet code°Ņ A¬†¬†°ĺArticle ID°Ņ1672-2531(2004)04-0042-04

Systematic Review of Clinical Evidence: the Efficacy of Stereotactic Aspiration in the Treatment of Cerebral Hemorrhage

°ĺAbstract°Ņ

Objective  To explore whether there is enough clinical evidence to confirm that stereotactic aspiration does more good than harm in patients with cerebral hemorrhage.  Method  A systematic review of all relevant clinical studies on stereotactic aspiration in the treatment of cerebral hemorrhage.  Results  Eight randomized controlled trials (RCTs) including 757 patients and 17 nonrandomized controlled studies including 1 766 patients, as well as 20 uncontrolled studies including 1 244 patients were identified . All studies reported positive results regarding the effects. However, the quality of the included studies were generally poor. The main problem was that most trials reported them as a RCT, but no description of the method of randomization.  Conclusions  Stereotactic aspiration in the treatment of cerebral hemorrhage is promising based on present evidence. However, at present, we can not draw definite conclusion whether the treatment does more good than harm compared with noninvasive medical treatment because of the poor quality of included studies. Therefore, more high quality RCTs are required.

(Received date£ļ2003-12-01 Revised date£ļ2004-01-05)

°ĺKey word°Ņ
 Cerebral hemorrhage; Aspiration ; Systematic review
°ĺReference°Ņ

[1]  Teernstra OPM, Evers SMAA, Lodder J, Leffers P, Franke CL, Blaauw G. Stereotactic treatment of intracerebral hematoma by means of a plasminogen activator: a muliticenter randomized controlled trial[J]. Stroke, 2003; 34(4): 968-974
[2]¬†¬†Xu JL, Wang WJ, Zhou JX, Zhao J. The comparison of stereotactic aspiration with conservative therapy for hypertensive intracerebral hematoma[J]. J Apoplexy and Nervous Diseases, 1993; 10£®2£©: 110-111
[3]  Chang JJ, Yang MX, Liu J. Analysis of 34 patients of saline flushed for cerebral hemorrhage[J]. Journal of Clinical neurology, 1996; 9(5): 304-305
[4]¬†¬†Wang SH. The treatment of stereotactic aspiration combined with saline flushed :analysis of 68 patients with intracerebral hematoma\[J]. Henan Medical Information, 1998£Ľ6£®3£©£ļ4-5
[5]¬†¬†Liang ZZ, He GX. The effect of stereotactic aspiration on hypertensive intracerebral hematoma[J]. Guangzhou Medical Journal, 1998; 29£®3£©£ļ20-21
[6]¬†¬†Fang YN, Lin JW, Li XF, Lin XS, Huang RX. The clinical analysis of prognosis of supratentorial intracerebral hematoma: the comparison of stereotactic aspiration with conservative therapy[J]. J Apoplexy and Nervous Diseases, 1999£Ľ16£®2£©£ļ98-99.
[7]¬†¬†He SL, Lin Y. Analysis of 56 patients with intracerebral hematoma by stereotactic treatment[J]. Chin J Nerv Ment Dis, 2001£Ľ27£®6£©£ļ464-465
[8]¬†¬†Xu K, Huang L, Zhang YF. The clinical study of minimally invasive surgery for hypertensive intracerebral hematoma[J]. Chin J Nerv Ment Dis, 2001£Ľ£®6£©£ļ444-446
[9]  Meng JM. Recommendation for clinical study of stroke[J]. Chinese Journal of Neurology and Psychiatry, 1988: 21(1): 57
[10]¬†Dennis MS, Burn JP, Sandercock PA. Long™≤term survival after first™≤ever stroke: the Oxfordshire Community Stroke Project[J]. Stroke, 1993; 24(6):796-800
[11]¬†Geoffery AD, Stephen MD. Surgery for Intracerebral Hemorrhage: An Evidence™≤Poor zone[J]. Stroke, 2003, 34(6): 1569-1570

 

LI Wei, LIU Ming*

Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China


ISSN 1672-2531
CN 51-1656/R
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